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The immune system and blood regeneration trust in hematopoietic stem cells (HSCs), that are critical due to their flexibility in cell differentiation into many blood cell types45. The utilization of these cells in bone marrow transplants represents a cornerstone in hematological therapies, providing a curative technique for ailments like leukemia a
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There have also been combined benefits from trials with regard to the utility of TMB. So far, no prospective scientific trials experienced demonstrated that collection of ICI treatment based upon a significant TMB more than reduced TMB improves OS.one,10 Most reports have evaluated TMB in precise tumors varieties, whereas KEYNOTE-158 evaluated TMB